References

Artichoke

First Study

  • Reference: American Botanical Council.
  • Date: September 30, 2008
  • Objective: Evaluate effect on plasma cholesterol concentration.
  • Methodology: Randomized, double-blind, placebo-controlled study.
  • Place: UK.
  • Patients Number: 75 Adults
  • Conclusion: Study indicates that consumption of 1280 mg ALE daily for 12 weeks has a modest but favorable statistically significant effect on plasma total cholesterol levels in hypercholesterolemic adults.

Second Study

  • Reference: American Botanical Council.
  • Date:  1998
  • Objective: Benefits of ALE in hypercholesterolemic,
    dyspepsia, and liver function.
  • Methodology: Randomized, double-blind, placebocontrolled study.
  • Place: Multicenter Study.
  • Patients Number: 557 Adults
  • Conclusion: Study indicates that consumption of
    1500 mg ALE daily for 43 days reduced cholesterol
    synthesis in the liver.
    • In related studies:
    • ALE had hepatoprotective and 10 mg/ml ALE
    protect hepatocytes from CCL4 toxicity in vitro.
    • ALE also appears to stimulate tissue regeneration
    & numbers of binuclear liver cells.

Curcuma (Turmeric)

First Study

  • Reference: Acta Med Inodnes / PubMed
  • Date: 2011
  • Objective: Established & novel NF-KB inihibtors
    effects on TLRS & HNSCC.
  • Methodology: Prospective Study
  • Place: Germany.
  • Conclusion: Curcumin has potent antiinflammatory effect and strong inhibition
    effect on NF-KB pathway

Second Study

  • Reference: Acta Med Inodnes / PubMed
  • Date: 2008
  • Objective: Effect of curcumin on lipid level in
    patients with acute coronary syndrome.
  • Methodology: Randomized, double-blind, placebocontrolled study.
  • Place: Indonesia
  • Patients Number: 557 Adults
  • Conclusion: Administration of low-dose
    curcumin showed a trend of reduction in
    total cholesterol level & LDL cholesterol
    levels in ASC patients.

Liquorice

First Study

  • Reference: Pyhtother Res / PubMed
  • Date: 2012
  • Objective: Efficacy of liquorice root extract in
    decreasing transaminase activities in NAFLD.
  • Methodology: Randomized, double-blind, placebocontrolled study.
  • Place: Iran.
  • Patients Number: 66 Adults.
  • Conclusion: Administration of liquorice
    root extract (2gm) for 2 months has
    significant impact on ALT & AST with
    statistical significance

Second Study

  • Reference: Oncology
  • Date: 2002
  • Objective: Preventing liver cirrhosis & HCC with
    glycyrrhizin (SNMC).
  • Methodology: Multiple.
  • Place: Japan.
  • Patients Number:Multiple
  • Conclusion: Administration of low-dose
    curcumin showed a trend of reduction in
    total cholesterol level & LDL cholesterol
    levels in ASC patients.

Milk Thistle (Mariana 90)

First Study

  • Reference: American Botanical Council
  • Date: 2005
  • Objective: Silymarin in the treatment of liver
    disease.
  • Methodology: Conservative Meta Analysis.

Second Study

  • Reference: American Botanical Council
  • Date: 2008
  • Objective: Silymarin as an adjunctive therapy in
    chemotherapy.

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